Shared cancer neoantigens: Making private matters public.
نویسندگان
چکیده
In this issue of JEM, Chheda et al. (https://doi.org/10.1084/jem.20171046) report that a conserved hotspot mutation associated with an aggressive form of brain cancer generates an immunogenic T cell epitope restricted by a common HLA subtype, thereby creating a "public" neoantigen.
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ورودعنوان ژورنال:
- The Journal of experimental medicine
دوره 215 1 شماره
صفحات -
تاریخ انتشار 2018